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Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology
Leptospira spp. are diderm (two membranes) bacteria that infect mammals causing leptospirosis, a public health problem with global implications. Thousands of people die every year due to leptospirosis, especially in developing countries with tropical climates. Prophylaxis is difficult due to multipl...
Autores principales: | Grassmann, André Alex, Kremer, Frederico Schmitt, dos Santos, Júlia Cougo, Souza, Jéssica Dias, Pinto, Luciano da Silva, McBride, Alan John Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406399/ https://www.ncbi.nlm.nih.gov/pubmed/28496441 http://dx.doi.org/10.3389/fimmu.2017.00463 |
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