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Inactive Gingipains from P. gingivalis Selectively Skews T Cells toward a Th17 Phenotype in an IL-6 Dependent Manner

Gingipain cysteine proteases are considered key virulence factors of Porphyromonas gingivalis. They significantly influence antibacterial and homeostatic functions of macrophages, neutrophils, the complement system, and cytokine networks. Recent data indicate the role of P. gingivalis in T cell diff...

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Detalles Bibliográficos
Autores principales: Glowczyk, Izabela, Wong, Alicia, Potempa, Barbara, Babyak, Olena, Lech, Maciej, Lamont, Richard J., Potempa, Jan, Koziel, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406403/
https://www.ncbi.nlm.nih.gov/pubmed/28497028
http://dx.doi.org/10.3389/fcimb.2017.00140