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CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria

Hypoxia is a characteristic of the tumor microenvironment and is known to contribute to tumor progression and treatment resistance. Hypoxia-inducible factor (HIF) dimeric transcription factors control the cellular response to reduced oxygenation by regulating the expression of genes involved in meta...

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Detalles Bibliográficos
Autores principales: Thomas, Luke W., Staples, Oliver, Turmaine, Mark, Ashcroft, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406405/
https://www.ncbi.nlm.nih.gov/pubmed/28497026
http://dx.doi.org/10.3389/fonc.2017.00071