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Tumor specific regulatory T cells in the bone marrow of breast cancer patients selectively upregulate the emigration receptor S1P1

Regulatory T cells (Treg) hamper anti-tumor T-cell responses resulting in reduced survival and failure of cancer immunotherapy. Among lymphoid organs, the bone marrow (BM) is a major site of Treg residence and recirculation. However, the process governing the emigration of Treg from BM into the circ...

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Detalles Bibliográficos
Autores principales: Rathinasamy, Anchana, Domschke, Christoph, Ge, Yingzi, Böhm, Hans-Henning, Dettling, Steffen, Jansen, David, Lasitschka, Felix, Umansky, Ludmila, Gräler, Markus H., Hartmann, Jennifer, Herold-Mende, Christel, Schuetz, Florian, Beckhove, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406429/
https://www.ncbi.nlm.nih.gov/pubmed/28224210
http://dx.doi.org/10.1007/s00262-017-1964-4