Lysophosphatidic Acid Is Associated with Atherosclerotic Plaque Instability by Regulating NF-κB Dependent Matrix Metalloproteinase-9 Expression via LPA(2) in Macrophages

Lysophosphatidic acid (LPA), one of the simplest phospholipid signaling molecules, participates in formation and disruption of atherosclerotic plaque. Matrix metalloproteinases (MMPs) contribute to atherosclerotic plaque rupture by involving in extracellular matrix (ECM) degradation and then thinnin...

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Detalles Bibliográficos
Autores principales: Gu, Chun, Wang, Fang, Zhao, Zhenwen, Wang, Hongyue, Cong, Xiangfeng, Chen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406459/
https://www.ncbi.nlm.nih.gov/pubmed/28496416
http://dx.doi.org/10.3389/fphys.2017.00266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406459/
https://www.ncbi.nlm.nih.gov/pubmed/28496416
http://dx.doi.org/10.3389/fphys.2017.00266

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