DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways

DBF4-dependent kinase (DDK) is a two-subunit kinase required for initiating DNA replication at individual origins and is composed of CDC7 kinase and its regulatory subunit DBF4. Both subunits are highly expressed in many diverse tumor cell lines and primary tumors, and this is correlated with poor p...

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Detalles Bibliográficos
Autores principales: Sasi, Nanda Kumar, Bhutkar, Arjun, Lanning, Nathan J., MacKeigan, Jeffrey P., Weinreich, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406526/
https://www.ncbi.nlm.nih.gov/pubmed/28448802
http://dx.doi.org/10.1016/j.neo.2017.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406526/
https://www.ncbi.nlm.nih.gov/pubmed/28448802
http://dx.doi.org/10.1016/j.neo.2017.03.001

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