Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy

Inhibition of immune checkpoint molecules, PD‐1 and CTLA4, has been shown to be a promising cancer treatment. PD‐1 and CTLA4 inhibit TCR and co‐stimulatory signals. The third T cell activation signal represents the signals from the cytokine receptors. The cytokine interferon‐γ (IFNγ) plays an import...

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Detalles Bibliográficos
Autores principales: Chikuma, Shunsuke, Kanamori, Mitsuhiro, Mise‐Omata, Setsuko, Yoshimura, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406529/
https://www.ncbi.nlm.nih.gov/pubmed/28188673
http://dx.doi.org/10.1111/cas.13194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406529/
https://www.ncbi.nlm.nih.gov/pubmed/28188673
http://dx.doi.org/10.1111/cas.13194

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