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Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
“Cellular senescence” is a state in which cells undergo irreversible cell cycle arrest in response to a variety of cellular stresses. Once cells senesce, they are strongly resistant to any mitogens, including oncogenic stimuli. Therefore, cellular senescence has been assumed to be a potent anticance...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406532/ https://www.ncbi.nlm.nih.gov/pubmed/28165648 http://dx.doi.org/10.1111/cas.13184 |