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Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease

INTRODUCTION: There is increasing evidence for the involvement of chronic inflammation and oxidative stress in the pathogenesis of Alzheimer's disease (AD). Nuclear factor erythroid 2-related factor 2 (Nrf2) is an anti-inflammatory transcription factor that regulates the oxidative stress defens...

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Detalles Bibliográficos
Autores principales: Fragoulis, Athanassios, Siegl, Stephanie, Fendt, Markus, Jansen, Sandra, Soppa, Ulf, Brandenburg, Lars-Ove, Pufe, Thomas, Weis, Joachim, Wruck, Christoph Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406548/
https://www.ncbi.nlm.nih.gov/pubmed/28448946
http://dx.doi.org/10.1016/j.redox.2017.04.024