Influence of the estrus cycle on the evaluation of a vaginal irritation study in intact and ovariectomized rats

When conducting vaginal irritation studies, ovariectomized rats or rabbits are typically used according to practical reports. In the present study, we evaluated the influence of the estrus cycle in a vaginal irritation study using intact rats and ovariectomized rats, which exhibit a late diestrus-li...

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Detalles Bibliográficos
Autores principales: Ishii, Aiko, Ogawa, Bunichiro, Koyama, Tomoko, Nakanishi, Yutaka, Sasaki, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406595/
https://www.ncbi.nlm.nih.gov/pubmed/28458454
http://dx.doi.org/10.1293/tox.2016-0059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406595/
https://www.ncbi.nlm.nih.gov/pubmed/28458454
http://dx.doi.org/10.1293/tox.2016-0059

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