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Molecular‐targeting therapies against quantitative abnormalities in gene expression with malignant tumors

Genetic mutations in exons of oncogenes and tumor‐suppressor genes causing qualitative abnormalities result in activation of the oncogenes and inactivation of the tumor‐suppressor genes, thereby causing cancer. In contrast, we have previously demonstrated that decreases in the RB promoter activity b...

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Detalles Bibliográficos
Autores principales: Sakai, Toshiyuki, Sowa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406604/
https://www.ncbi.nlm.nih.gov/pubmed/28178388
http://dx.doi.org/10.1111/cas.13188