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Ketamine augmentation of electroconvulsive therapy to improve neuropsychological and clinical outcomes in depression (Ketamine-ECT): a multicentre, double-blind, randomised, parallel-group, superiority trial

BACKGROUND: The use of electroconvulsive therapy (ECT) is limited by concerns about its cognitive adverse effects. Preliminary evidence suggests that administering the glutamate antagonist ketamine with ECT might alleviate cognitive adverse effects and accelerate symptomatic improvement; we tested t...

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Detalles Bibliográficos
Autores principales: Anderson, Ian M, Blamire, Andrew, Branton, Tim, Clark, Ross, Downey, Darragh, Dunn, Graham, Easton, Andrew, Elliott, Rebecca, Elwell, Clare, Hayden, Katherine, Holland, Fiona, Karim, Salman, Loo, Colleen, Lowe, Jo, Nair, Rajesh, Oakley, Timothy, Prakash, Antony, Sharma, Parveen K, Williams, Stephen R, McAllister-Williams, R Hamish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406618/
https://www.ncbi.nlm.nih.gov/pubmed/28359862
http://dx.doi.org/10.1016/S2215-0366(17)30077-9