NG2 Proteoglycan Enhances Brain Tumor Progression by Promoting Beta-1 Integrin Activation in both Cis and Trans Orientations

By physically interacting with beta-1 integrins, the NG2 proteoglycan enhances activation of the integrin heterodimers. In glioma cells, co-localization of NG2 and α3β1 integrin in individual cells (cis interaction) can be demonstrated by immunolabeling, and the NG2-integrin interaction can be confi...

Descripción completa

Detalles Bibliográficos
Autor principal: Stallcup, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406706/
https://www.ncbi.nlm.nih.gov/pubmed/28362324
http://dx.doi.org/10.3390/cancers9040031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406706/
https://www.ncbi.nlm.nih.gov/pubmed/28362324
http://dx.doi.org/10.3390/cancers9040031

Ejemplares similares