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Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

Decoquinate nanoparticle and microparticle suspended in an oily vehicle to retard drug release are evaluated for long-term malaria prophylaxis. Pharmacokinetic studies in normal animals and antimalarial efficacy in liver stage malaria mice were conducted at various single intramuscular-decoquinate d...

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Detalles Bibliográficos
Autores principales:	Li, Qigui, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Roncal, Norma, Zhang, Ping, Vuong, Chau, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Read, Lisa, Hickman, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406721/ https://www.ncbi.nlm.nih.gov/pubmed/28491482 http://dx.doi.org/10.1155/2017/7508291

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