Modeling and Targeting MYC Genes in Childhood Brain Tumors

Brain tumors are the second most common group of childhood cancers, accounting for about 20%–25% of all pediatric tumors. Deregulated expression of the MYC family of transcription factors, particularly c-MYC and MYCN genes, has been found in many of these neoplasms, and their expression levels are o...

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Detalles Bibliográficos
Autores principales: Hutter, Sonja, Bolin, Sara, Weishaupt, Holger, Swartling, Fredrik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406854/
https://www.ncbi.nlm.nih.gov/pubmed/28333115
http://dx.doi.org/10.3390/genes8040107