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Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication

The replicative helicase unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. In eukaryotes, the replicative helicase is composed of the Cdc45 protein, the heterohexameric ring-shaped Mcm2-7 complex, and the tetrameric G...

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Detalles Bibliográficos
Autores principales: Martinez, Matthew P., Wacker, Amanda L., Bruck, Irina, Kaplan, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406864/
https://www.ncbi.nlm.nih.gov/pubmed/28383499
http://dx.doi.org/10.3390/genes8040117