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Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling
The transcription factor and cell growth regulator MYC is potently oncogenic and estimated to contribute to most cancers. Decades of attempts to therapeutically target MYC directly have not resulted in feasible clinical applications, and efforts have moved toward indirectly targeting MYC expression,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406865/ https://www.ncbi.nlm.nih.gov/pubmed/28398229 http://dx.doi.org/10.3390/genes8040118 |