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Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling

The transcription factor and cell growth regulator MYC is potently oncogenic and estimated to contribute to most cancers. Decades of attempts to therapeutically target MYC directly have not resulted in feasible clinical applications, and efforts have moved toward indirectly targeting MYC expression,...

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Detalles Bibliográficos
Autores principales: Zaytseva, Olga, Quinn, Leonie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406865/
https://www.ncbi.nlm.nih.gov/pubmed/28398229
http://dx.doi.org/10.3390/genes8040118