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Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes

BACKGROUND: The growth factor receptor network (GFRN) plays a significant role in driving key oncogenic processes. However, assessment of global GFRN activity is challenging due to complex crosstalk among GFRN components, or pathways, and the inability to study complex signaling networks in patient...

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Detalles Bibliográficos
Autores principales: Rahman, Mumtahena, MacNeil, Shelley M., Jenkins, David F., Shrestha, Gajendra, Wyatt, Sydney R., McQuerry, Jasmine A., Piccolo, Stephen R., Heiser, Laura M., Gray, Joe W., Johnson, W. Evan, Bild, Andrea H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406893/
https://www.ncbi.nlm.nih.gov/pubmed/28446242
http://dx.doi.org/10.1186/s13073-017-0429-x