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Metabolic engineering strategies for optimizing acetate reduction, ethanol yield and osmotolerance in Saccharomyces cerevisiae

BACKGROUND: Glycerol, whose formation contributes to cellular redox balancing and osmoregulation in Saccharomyces cerevisiae, is an important by-product of yeast-based bioethanol production. Replacing the glycerol pathway by an engineered pathway for NAD(+)-dependent acetate reduction has been shown...

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Detalles Bibliográficos
Autores principales: Papapetridis, Ioannis, van Dijk, Marlous, van Maris, Antonius J. A., Pronk, Jack T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406903/
https://www.ncbi.nlm.nih.gov/pubmed/28450888
http://dx.doi.org/10.1186/s13068-017-0791-3