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Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration

BACKGROUND: Three-dimensional cultured clumps of a mesenchymal stem cell (MSC)/extracellular matrix (ECM) complex (C-MSC) consists of cells and self-produced ECM. C-MSC can regulate the cellular function in vitro and induce successful bone regeneration using ECM as a cell scaffold. Potentiating the...

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Detalles Bibliográficos
Autores principales: Takeshita, Kei, Motoike, Souta, Kajiya, Mikihito, Komatsu, Nao, Takewaki, Manabu, Ouhara, Kazuhisa, Iwata, Tomoyuki, Takeda, Katsuhiro, Mizuno, Noriyoshi, Fujita, Tsuyoshi, Kurihara, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406942/
https://www.ncbi.nlm.nih.gov/pubmed/28446226
http://dx.doi.org/10.1186/s13287-017-0550-1