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Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration
BACKGROUND: Three-dimensional cultured clumps of a mesenchymal stem cell (MSC)/extracellular matrix (ECM) complex (C-MSC) consists of cells and self-produced ECM. C-MSC can regulate the cellular function in vitro and induce successful bone regeneration using ECM as a cell scaffold. Potentiating the...
Autores principales: | Takeshita, Kei, Motoike, Souta, Kajiya, Mikihito, Komatsu, Nao, Takewaki, Manabu, Ouhara, Kazuhisa, Iwata, Tomoyuki, Takeda, Katsuhiro, Mizuno, Noriyoshi, Fujita, Tsuyoshi, Kurihara, Hidemi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406942/ https://www.ncbi.nlm.nih.gov/pubmed/28446226 http://dx.doi.org/10.1186/s13287-017-0550-1 |
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