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Fingolimod attenuates experimental autoimmune neuritis and contributes to Schwann cell-mediated axonal protection

BACKGROUND: Fingolimod, a sphingosine-1-phosphate receptor modulator with well-described immunomodulatory properties involving peripheral immune cell trafficking, was the first oral agent approved for the treatment of relapsing remitting multiple sclerosis. Analogous immunomodulatory treatment optio...

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Detalles Bibliográficos
Autores principales: Ambrosius, Björn, Pitarokoili, Kalliopi, Schrewe, Lisa, Pedreiturria, Xiomara, Motte, Jeremias, Gold, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406994/
https://www.ncbi.nlm.nih.gov/pubmed/28446186
http://dx.doi.org/10.1186/s12974-017-0864-z