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Immunosuppressive capacity of mesenchymal stem cells correlates with metabolic activity and can be enhanced by valproic acid

BACKGROUND: Mesenchymal stem cells (MSCs) have entered the clinic as an Advanced Therapy Medicinal Product and are currently evaluated in a wide range of studies for tissue regeneration or in autoimmune disorders. Various efforts have been made to standardize and optimize expansion and manufacturing...

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Detalles Bibliográficos
Autores principales: Killer, Madeleine C., Nold, Philipp, Henkenius, Katharina, Fritz, Lea, Riedlinger, Tabea, Barckhausen, Christina, Frech, Miriam, Hackstein, Holger, Neubauer, Andreas, Brendel, Cornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406996/
https://www.ncbi.nlm.nih.gov/pubmed/28446224
http://dx.doi.org/10.1186/s13287-017-0553-y