SCALE: modeling allele-specific gene expression by single-cell RNA sequencing

Allele-specific expression is traditionally studied by bulk RNA sequencing, which measures average expression across cells. Single-cell RNA sequencing allows the comparison of expression distribution between the two alleles of a diploid organism and the characterization of allele-specific bursting....

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Detalles Bibliográficos
Autores principales: Jiang, Yuchao, Zhang, Nancy R., Li, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407026/
https://www.ncbi.nlm.nih.gov/pubmed/28446220
http://dx.doi.org/10.1186/s13059-017-1200-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407026/
https://www.ncbi.nlm.nih.gov/pubmed/28446220
http://dx.doi.org/10.1186/s13059-017-1200-8

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