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SCALE: modeling allele-specific gene expression by single-cell RNA sequencing
Allele-specific expression is traditionally studied by bulk RNA sequencing, which measures average expression across cells. Single-cell RNA sequencing allows the comparison of expression distribution between the two alleles of a diploid organism and the characterization of allele-specific bursting....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407026/ https://www.ncbi.nlm.nih.gov/pubmed/28446220 http://dx.doi.org/10.1186/s13059-017-1200-8 |