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Impact of tramadol and morphine abuse on the activities of acetylcholine esterase, Na+/K+-ATPase and related parameters in cerebral cortices of male adult rats

OBJECTIVE: To determine the effect of the most commonly abused drugs (tramadol and morphine), on acetylcholine esterase (AChE), Na(+)/K(+)-ATPase activities and related parameters, Na(+) and K(+) as biomarkers of neurotoxicity. METHODS: Tramadol - as a weak μ opioid receptor agonist- and morphine -...

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Detalles Bibliográficos
Autores principales: El-Hamid Mohamed Elwy, Abd, Tabl, Ghada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Electronic physician 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407239/
https://www.ncbi.nlm.nih.gov/pubmed/28461881
http://dx.doi.org/10.19082/4027