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Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron‐Like SH‐SY5Y and Microglia‐Like BV2

BACKGROUND: Ethanol (EtOH) consumption leads to an increase of proinflammatory signaling via activation of Toll‐like receptors (TLRs) such as TLR3 and TLR4 that leads to kinase activation (ERK1/2, p38, TBK1), transcription factor activation (NF κB, IRF3), and increased transcription of proinflammato...

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Detalles Bibliográficos
Autores principales: Lawrimore, Colleen J., Crews, Fulton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407472/
https://www.ncbi.nlm.nih.gov/pubmed/28273337
http://dx.doi.org/10.1111/acer.13368