Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various Leishmania species possess similar pyrimidine transpo...

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Detalles Bibliográficos
Autores principales: Alzahrani, Khalid J.H., Ali, Juma A.M., Eze, Anthonius A., Looi, Wan Limm, Tagoe, Daniel N.A., Creek, Darren J., Barrett, Michael P., de Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407577/
https://www.ncbi.nlm.nih.gov/pubmed/28453984
http://dx.doi.org/10.1016/j.ijpddr.2017.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407577/
https://www.ncbi.nlm.nih.gov/pubmed/28453984
http://dx.doi.org/10.1016/j.ijpddr.2017.04.003

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