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Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various Leishmania species possess similar pyrimidine transpo...

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Detalles Bibliográficos
Autores principales:	Alzahrani, Khalid J.H., Ali, Juma A.M., Eze, Anthonius A., Looi, Wan Limm, Tagoe, Daniel N.A., Creek, Darren J., Barrett, Michael P., de Koning, Harry P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407577/ https://www.ncbi.nlm.nih.gov/pubmed/28453984 http://dx.doi.org/10.1016/j.ijpddr.2017.04.003

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