Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure

Cigarette smoking (CS), the main risk factor for COPD (chronic obstructive pulmonary disease) in developed countries, decreases alveolar macrophages (AM) clearance of both apoptotic cells and bacterial pathogens. This global deficit of AM engulfment may explain why active smokers have worse outcomes...

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Detalles Bibliográficos
Autores principales: Serban, Karina A., Petrusca, Daniela N., Mikosz, Andrew, Poirier, Christophe, Lockett, Angelia D., Saint, Lauren, Justice, Matthew J., Twigg, Homer L., Campos, Michael A., Petrache, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407578/
https://www.ncbi.nlm.nih.gov/pubmed/28448535
http://dx.doi.org/10.1371/journal.pone.0176073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407578/
https://www.ncbi.nlm.nih.gov/pubmed/28448535
http://dx.doi.org/10.1371/journal.pone.0176073

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