Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms

BACKGROUND: Fatty-acid-binding proteins (FABPs) are intracellular carriers for endocannabinoids, N-acylethanolamines, and related lipids. Previous work indicates that systemically administered FABP5 inhibitors produce analgesia in models of inflammatory pain. It is currently not known whether FABP i...

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Detalles Bibliográficos
Autores principales: Peng, Xiaoxue, Studholme, Keith, Kanjiya, Martha P, Luk, Jennifer, Bogdan, Diane, Elmes, Matthew W, Carbonetti, Gregory, Tong, Simon, Gary Teng, Yu-Han, Rizzo, Robert C, Li, Huilin, Deutsch, Dale G, Ojima, Iwao, Rebecchi, Mario J, Puopolo, Michelino, Kaczocha, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407663/
https://www.ncbi.nlm.nih.gov/pubmed/28326944
http://dx.doi.org/10.1177/1744806917697007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407663/
https://www.ncbi.nlm.nih.gov/pubmed/28326944
http://dx.doi.org/10.1177/1744806917697007

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