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miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6

BACKGROUND: MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investigated in bronchial epithelial cells in vitro and in vivo. METHODS: Using in sil...

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Detalles Bibliográficos
Autores principales: Oglesby, Irene K, Agrawal, Raman, Mall, Marcus A, McElvaney, Noel G, Greene, Catherine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407678/
https://www.ncbi.nlm.nih.gov/pubmed/26542291
http://dx.doi.org/10.1186/s40348-014-0012-0