A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection

We present two minimally invasive microsurgical techniques in rodents for specific drug delivery into the middle ear so that it may reach the inner ear. The first procedure consists of perforation of the tympanic bulla, termed bullostomy; the second one is a transtympanic injection. Both emulate hum...

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Detalles Bibliográficos
Autores principales: Murillo-Cuesta, Silvia, Vallecillo, Néstor, Cediel, Rafael, Celaya, Adelaida M., Lassaletta, Luis, Varela-Nieto, Isabel, Contreras, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407703/
https://www.ncbi.nlm.nih.gov/pubmed/28362376
http://dx.doi.org/10.3791/54951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407703/
https://www.ncbi.nlm.nih.gov/pubmed/28362376
http://dx.doi.org/10.3791/54951

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