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A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
We present two minimally invasive microsurgical techniques in rodents for specific drug delivery into the middle ear so that it may reach the inner ear. The first procedure consists of perforation of the tympanic bulla, termed bullostomy; the second one is a transtympanic injection. Both emulate hum...
Autores principales: | Murillo-Cuesta, Silvia, Vallecillo, Néstor, Cediel, Rafael, Celaya, Adelaida M., Lassaletta, Luis, Varela-Nieto, Isabel, Contreras, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407703/ https://www.ncbi.nlm.nih.gov/pubmed/28362376 http://dx.doi.org/10.3791/54951 |
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