Engineering chimeric human and mouse major histocompatibility complex (MHC) class I tetramers for the production of T-cell receptor (TCR) mimic antibodies

Therapeutic monoclonal antibodies targeting cell surface or secreted antigens are among the most effective classes of novel immunotherapies. However, the majority of human proteins and established cancer biomarkers are intracellular. Peptides derived from these intracellular proteins are presented o...

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Detalles Bibliográficos
Autores principales: Li, Demin, Bentley, Carol, Yates, Jenna, Salimi, Maryam, Greig, Jenny, Wiblin, Sarah, Hassanali, Tasneem, Banham, Alison H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407768/
https://www.ncbi.nlm.nih.gov/pubmed/28448627
http://dx.doi.org/10.1371/journal.pone.0176642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407768/
https://www.ncbi.nlm.nih.gov/pubmed/28448627
http://dx.doi.org/10.1371/journal.pone.0176642

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