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Pyridoxal phosphate synthases PdxS/PdxT are required for Actinobacillus pleuropneumoniae viability, stress tolerance and virulence

Pyridoxal 5’-phosphate (PLP) is an essential cofactor for numerous enzymes involved in a diversity of cellular processes in living organisms. Previous analysis of the Actinobacillus pleuropneumoniae S-8 genome sequence revealed the presence of pdxS and pdxT genes, which are implicated in deoxyxylulo...

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Detalles Bibliográficos
Autores principales: Xie, Fang, Li, Gang, Wang, Yalei, Zhang, Yanhe, Zhou, Long, Wang, Chengcheng, Liu, Shuanghong, Liu, Siguo, Wang, Chunlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407770/
https://www.ncbi.nlm.nih.gov/pubmed/28448619
http://dx.doi.org/10.1371/journal.pone.0176374