Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice

The aim of this study was to determine whether calcium potentiates acute carbon tetrachloride (CCl(4)) -induced toxicity. Elevated calcium levels were induced in mice by pre-treatment with cholecalciferol (vitamin D3; V.D3), a compound that has previously been shown to induce hypercalcemia in human...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshioka, Hiroki, Usuda, Haruki, Miura, Nobuhiko, Fukuishi, Nobuyuki, Nonogaki, Tsunemasa, Onosaka, Satomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407844/
https://www.ncbi.nlm.nih.gov/pubmed/28448545
http://dx.doi.org/10.1371/journal.pone.0176524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407844/
https://www.ncbi.nlm.nih.gov/pubmed/28448545
http://dx.doi.org/10.1371/journal.pone.0176524

Ejemplares similares