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Trypanosoma brucei TbIF1 inhibits the essential F(1)-ATPase in the infectious form of the parasite

The mitochondrial (mt) F(o)F(1)-ATP synthase of the digenetic parasite, Trypanosoma brucei, generates ATP during the insect procyclic form (PF), but becomes a perpetual consumer of ATP in the mammalian bloodstream form (BF), which lacks a canonical respiratory chain. This unconventional dependence o...

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Detalles Bibliográficos
Autores principales: Panicucci, Brian, Gahura, Ondřej, Zíková, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407850/
https://www.ncbi.nlm.nih.gov/pubmed/28414727
http://dx.doi.org/10.1371/journal.pntd.0005552