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Trypanosoma brucei TbIF1 inhibits the essential F(1)-ATPase in the infectious form of the parasite
The mitochondrial (mt) F(o)F(1)-ATP synthase of the digenetic parasite, Trypanosoma brucei, generates ATP during the insect procyclic form (PF), but becomes a perpetual consumer of ATP in the mammalian bloodstream form (BF), which lacks a canonical respiratory chain. This unconventional dependence o...
Autores principales: | Panicucci, Brian, Gahura, Ondřej, Zíková, Alena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407850/ https://www.ncbi.nlm.nih.gov/pubmed/28414727 http://dx.doi.org/10.1371/journal.pntd.0005552 |
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