AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation

Dietary restriction increases the longevity of many organisms, but the cell signaling and organellar mechanisms underlying this capability are unclear. We demonstrate that to permit long-term survival in response to sudden glucose depletion, yeast cells activate lipid-droplet (LD) consumption throug...

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Detalles Bibliográficos
Autores principales: Seo, Arnold Y, Lau, Pick-Wei, Feliciano, Daniel, Sengupta, Prabuddha, Gros, Mark A Le, Cinquin, Bertrand, Larabell, Carolyn A, Lippincott-Schwartz, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407857/
https://www.ncbi.nlm.nih.gov/pubmed/28394250
http://dx.doi.org/10.7554/eLife.21690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407857/
https://www.ncbi.nlm.nih.gov/pubmed/28394250
http://dx.doi.org/10.7554/eLife.21690

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