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Enhanced dereplication of fungal cultures via use of mass defect filtering

Effective and rapid dereplication is a hallmark of present-day drug discovery from natural sources. This project strove to both decrease the time and expand the structural diversity associated with dereplication methodologies. A 5 min liquid chromatographic run time employing heated electrospray ion...

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Detalles Bibliográficos
Autores principales: Paguigan, Noemi D, El-Elimat, Tamam, Kao, Diana, Raja, Huzefa A, Pearce, Cedric J, Oberlies, Nicholas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407915/
https://www.ncbi.nlm.nih.gov/pubmed/28074050
http://dx.doi.org/10.1038/ja.2016.145