Phospholipase D from Loxosceles laeta Spider Venom Induces IL-6, IL-8, CXCL1/GRO-α, and CCL2/MCP-1 Production in Human Skin Fibroblasts and Stimulates Monocytes Migration

Cutaneous loxoscelism envenomation by Loxosceles spiders is characterized by the development of a dermonecrotic lesion, strong inflammatory response, the production of pro-inflammatory mediators, and leukocyte migration to the bite site. The role of phospholipase D (PLD) from Loxosceles in the recru...

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Detalles Bibliográficos
Autores principales: Rojas, José M., Arán-Sekul, Tomás, Cortés, Emmanuel, Jaldín, Romina, Ordenes, Kely, Orrego, Patricio R., González, Jorge, Araya, Jorge E., Catalán, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408199/
https://www.ncbi.nlm.nih.gov/pubmed/28379166
http://dx.doi.org/10.3390/toxins9040125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408199/
https://www.ncbi.nlm.nih.gov/pubmed/28379166
http://dx.doi.org/10.3390/toxins9040125

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