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Establishment of the Inducible Tet-On System for the Activation of the Silent Trichosetin Gene Cluster in Fusarium fujikuroi

The PKS-NRPS-derived tetramic acid equisetin and its N-desmethyl derivative trichosetin exhibit remarkable biological activities against a variety of organisms, including plants and bacteria, e.g., Staphylococcus aureus. The equisetin biosynthetic gene cluster was first described in Fusarium heteros...

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Detalles Bibliográficos
Autores principales: Janevska, Slavica, Arndt, Birgit, Baumann, Leonie, Apken, Lisa Helene, Mauriz Marques, Lucas Maciel, Humpf, Hans-Ulrich, Tudzynski, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408200/
https://www.ncbi.nlm.nih.gov/pubmed/28379186
http://dx.doi.org/10.3390/toxins9040126