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Novel lnc RNA regulated by HIF‐1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia

Chronic tubulointerstitial hypoxia plays an important role as the final common pathway to end‐stage renal disease. HIF‐1 (hypoxia‐inducible factor‐1) is a master transcriptional factor under hypoxia, regulating downstream target genes. Genome‐wide analysis of HIF‐1 binding sites using high‐throughpu...

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Detalles Bibliográficos
Autores principales: Mimura, Imari, Hirakawa, Yosuke, Kanki, Yasuharu, Kushida, Natsuki, Nakaki, Ryo, Suzuki, Yutaka, Tanaka, Tetsuhiro, Aburatani, Hiroyuki, Nangaku, Masaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408278/
https://www.ncbi.nlm.nih.gov/pubmed/28420760
http://dx.doi.org/10.14814/phy2.13203