Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis

The three‐membered RUNX gene family includes RUNX1, a major mutational target in human leukemias, and displays hallmarks of both tumor suppressors and oncogenes. In mouse models, the Runx genes appear to act as conditional oncogenes, as ectopic expression is growth suppressive in normal cells but dr...

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Detalles Bibliográficos
Autores principales: Kilbey, A., Terry, A., Wotton, S., Borland, G., Zhang, Q., Mackay, N., McDonald, A., Bell, M., Wakelam, M.J.O., Cameron, E.R., Neil, J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408393/
https://www.ncbi.nlm.nih.gov/pubmed/27869314
http://dx.doi.org/10.1002/jcb.25802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408393/
https://www.ncbi.nlm.nih.gov/pubmed/27869314
http://dx.doi.org/10.1002/jcb.25802

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