Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study

BACKGROUND: Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown. METHODS: As part of a prospective observational study, enrolment...

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Detalles Bibliográficos
Autores principales: Plewes, Katherine, Kingston, Hugh W.F., Ghose, Aniruddha, Maude, Richard J., Herdman, M. Trent, Leopold, Stije J., Ishioka, Haruhiko, Hasan, Md. Mahtab Uddin, Haider, Md. Shafiul, Alam, Shamsul, Piera, Kim A., Charunwatthana, Prakaykaew, Silamut, Kamolrat, Yeo, Tsin W., Faiz, Md. Abul, Lee, Sue J, Mukaka, Mavuto, Turner, Gareth D.H., Anstey, Nicholas M., Jackson Roberts, L., White, Nicholas J., Day, Nicholas P.J., Hossain, Md. Amir, Dondorp, Arjen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408414/
https://www.ncbi.nlm.nih.gov/pubmed/28449641
http://dx.doi.org/10.1186/s12879-017-2373-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408414/
https://www.ncbi.nlm.nih.gov/pubmed/28449641
http://dx.doi.org/10.1186/s12879-017-2373-1

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