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Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study
BACKGROUND: Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown. METHODS: As part of a prospective observational study, enrolment...
Autores principales: | Plewes, Katherine, Kingston, Hugh W.F., Ghose, Aniruddha, Maude, Richard J., Herdman, M. Trent, Leopold, Stije J., Ishioka, Haruhiko, Hasan, Md. Mahtab Uddin, Haider, Md. Shafiul, Alam, Shamsul, Piera, Kim A., Charunwatthana, Prakaykaew, Silamut, Kamolrat, Yeo, Tsin W., Faiz, Md. Abul, Lee, Sue J, Mukaka, Mavuto, Turner, Gareth D.H., Anstey, Nicholas M., Jackson Roberts, L., White, Nicholas J., Day, Nicholas P.J., Hossain, Md. Amir, Dondorp, Arjen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408414/ https://www.ncbi.nlm.nih.gov/pubmed/28449641 http://dx.doi.org/10.1186/s12879-017-2373-1 |
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