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PEAR1 is not a major susceptibility gene for cardiovascular disease in a Flemish population

BACKGROUND: Platelet Endothelial Aggregation Receptor 1 (PEAR1), a membrane protein highly expressed in platelets and endothelial cells, plays a role in platelet contact-induced activation, sustained platelet aggregation and endothelial function. Previous reports implicate PEAR1 rs12041331 as a vari...

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Detalles Bibliográficos
Autores principales: Yang, Wen-Yi, Petit, Thibault, Cauwenberghs, Nicholas, Zhang, Zhen-Yu, Sheng, Chang-Sheng, Thijs, Lutgarde, Salvi, Erika, Izzi, Benedetta, Vandenbriele, Christophe, Wei, Fang-Fei, Gu, Yu-Mei, Jacobs, Lotte, Citterio, Lorena, Delli Carpini, Simona, Barlassina, Cristina, Cusi, Daniele, Hoylaerts, Marc F., Verhamme, Peter, Kuznetsova, Tatiana, Staessen, Jan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408434/
https://www.ncbi.nlm.nih.gov/pubmed/28449647
http://dx.doi.org/10.1186/s12881-017-0411-x