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Influence of subject discontinuation on long-term nonvertebral fracture rate in the denosumab FREEDOM Extension study
BACKGROUND: Denosumab treatment for up to 8 years in the FREEDOM study and Extension was associated with low fracture incidence. It was not clear whether subjects who discontinued during the study conduct had a higher risk of fracture than those who remained enrolled, thereby underestimating the tru...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408481/ https://www.ncbi.nlm.nih.gov/pubmed/28449657 http://dx.doi.org/10.1186/s12891-017-1520-6 |