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The differential effects of FTY720 on functional recovery and infarct size following myocardial ischaemia/ reperfusion

AIM: The aim of this study was to evaluate the effects of the sphingosine analogue, FTY720 (Fingolimod), on the outcomes of myocardial ischaemia/reperfusion (I/R) injury. METHODS: Two concentrations of FTY720 (1 or 2.5 μM) were administered either prior to (PreFTY), or following (PostFTY) 20 minutes...

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Detalles Bibliográficos
Autores principales: van Vuuren, Derick, Marais, Erna, Genade, Sonia, Lochner, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408499/
https://www.ncbi.nlm.nih.gov/pubmed/27966000
http://dx.doi.org/10.5830/CVJA-2016-039